[Home ] [Archive]    
:: Main :: About :: Current Issue :: Archive :: Search :: Submit ::
Main Menu
Journal Information::
Articles archive::
For Authors::
For Reviewers::
Contact us::
Site Facilities::
Publication Ethics::
Indexed & full text in


Journal's Impact Factor


             "If you have any questions or concerns, please contact us by email

Journal`s Impact Factor 2023:0.985
Journal's Impact Factor ISC 2020: 0.476


Search in website

Advanced Search
Receive site information
Enter your Email in the following box to receive the site news and information.
Abstract in

 پایگاه استنادی علوم جهان اسلام (ISC)

پایگاه اطلاعات جهاد دانشگاهی (SID) 

بانک نشریات کشور (مگیران)




Journal DOI

Journal DOI


:: Volume 21, Issue 3 (2022) ::
IJFS 2022, 21 Back to browse issues page
Research Article: Hepatic CYP450 gene expression, hematological and biochemical indices in Caspian roach (Rutilus caspius) induced by Endosulfan
M. Tajari , A. Kamali * , H. Rajabi Islami , H. Paknejad
Islamic azad universityof Tehran , kamali.abolghasem@gmail.com
Abstract:   (1175 Views)
Endosulfan is one of the organochlorine pesticides which has been used worldwide for decades. The purpose of the present study was to investigate the effect of endosulfan on hematological and P450 gene expression in Rutilus caspius. Fish were exposed to the 10% and 20% LC50 for 21 days and were sampled on days 1, 7, 14 and 21. Results showed that there were significant differences in hematological parameters among the control and treated fish (p<0.05). The highest amount of Hb, Ht and RBC was observed in the control, while WBC was highest in the 20% endosulfan treated group on day 21. According to the results alkaline phosphatase, aspartate aminotransaminase and alanine amino transaminase levels increased during the experiment. The highest levels were observed with 20% endosulfan on day 14 which were significantly different with those in the control (p<0.05). In addition, the CYP450 gene expression had the same results. We conclude that exposure to the endosulfan (especially 20%) can enhance the innate immune system in Rutilus caspius.
Keywords: Endosulfan, Hematological, Gene expression, Rutilus caspius.
Full-Text [PDF 321 kb]   (565 Downloads)    
Type of Study: Orginal research papers | Subject: Biology & physiology
Received: 2018/07/19 | Accepted: 2018/12/17 | Published: 2022/08/13
Send email to the article author

Add your comments about this article
Your username or Email:


XML     Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Tajari M, Kamali A, Rajabi Islami H, Paknejad H. Research Article: Hepatic CYP450 gene expression, hematological and biochemical indices in Caspian roach (Rutilus caspius) induced by Endosulfan. IJFS 2022; 21 (3) :758-768
URL: http://jifro.ir/article-1-3529-en.html

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 21, Issue 3 (2022) Back to browse issues page
Iranian Journal of Fisheries Sciences Iranian Journal of Fisheries Sciences
Persian site map - English site map - Created in 0.05 seconds with 45 queries by YEKTAWEB 4645