[Home ] [Archive]    
:: Main :: About :: Current Issue :: Archive :: Search :: Submit ::
:: Volume 21, Issue 3 (2022) ::
IJFS 2022, 21 Back to browse issues page
Research Article: Hepatic CYP450 gene expression, hematological and biochemical indices in Caspian roach (Rutilus caspius) induced by Endosulfan
M. Tajari, A. Kamali *, H. Rajabi Islami, H. Paknejad
Islamic azad universityof Tehran , kamali.abolghasem@gmail.com
Abstract:   (267 Views)
Endosulfan is one of the organochlorine pesticides which has been used worldwide for decades. The purpose of the present study was to investigate the effect of endosulfan on hematological and P450 gene expression in Rutilus caspius. Fish were exposed to the 10% and 20% LC50 for 21 days and were sampled on days 1, 7, 14 and 21. Results showed that there were significant differences in hematological parameters among the control and treated fish (p<0.05). The highest amount of Hb, Ht and RBC was observed in the control, while WBC was highest in the 20% endosulfan treated group on day 21. According to the results alkaline phosphatase, aspartate aminotransaminase and alanine amino transaminase levels increased during the experiment. The highest levels were observed with 20% endosulfan on day 14 which were significantly different with those in the control (p<0.05). In addition, the CYP450 gene expression had the same results. We conclude that exposure to the endosulfan (especially 20%) can enhance the innate immune system in Rutilus caspius.
Keywords: Endosulfan, Hematological, Gene expression, Rutilus caspius.
Full-Text [PDF 321 kb]   (105 Downloads)    
Type of Study: Orginal research papers | Subject: Biology & physiology
Received: 2018/07/19 | Accepted: 2018/12/17 | Published: 2022/08/13
Send email to the article author

Add your comments about this article
Your username or Email:

CAPTCHA


XML     Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Tajari M, Kamali A, Rajabi Islami H, Paknejad H. Research Article: Hepatic CYP450 gene expression, hematological and biochemical indices in Caspian roach (Rutilus caspius) induced by Endosulfan. IJFS. 2022; 21 (3) :758-768
URL: http://jifro.ir/article-1-3529-en.html


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 21, Issue 3 (2022) Back to browse issues page
Iranian Journal of Fisheries Sciences Iranian Journal of Fisheries Sciences
Persian site map - English site map - Created in 0.04 seconds with 30 queries by YEKTAWEB 4447