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:: دوره 21، شماره 6 - ( 1401 ) ::
جلد 21 شماره 6 صفحات 1396-1383 برگشت به فهرست نسخه ها
Research Article: The effect of Letrozole and Letrozole-Chitosan nanoparticles on masculinization of Rainbow trout larvae (Oncorhynchus mykiss)
چکیده:   (1155 مشاهده)
This study aimed to investigate the efficiency of conjugating chitosan nanoparticles to letrozole (LET) on masculinization of rainbow trout larvae, Oncorhynchus mykiss. For this purpose, two treatments of LET, 1.5 and 3 mg/kg food, and two treatments of letrozole-chitosan nanoparticles (LET-CS), 0.5 and 1.5 mg/kg were performed with a control group. Treatments began immediately after active larval swimming and continued for 60 days. The results showed that the amount of testosterone during the trial increased significantly (p<0.05), so that the highest amount of testosterone was observed in 3 mg/kg LET and 1.5 mg/kg LET-CS. However, estradiol was untraceable in all treatments. About 66.6, 73.33, 73.33, 76.66 and 43.33% males were observed in 1.5 mg/kg LET, 3 mg/kg LET, 0.5 mg/kg LET-CS, 1.5 mg/kg LET-CS and control, respectively. Despite the drug dosage in LET-CS treatments was half that of LET treatments, the sex ratio did not change among treatments (p≥ 0.05), which showed a positive effect of CS in effectiveness of LET. In general, it can be stated that using CS for the administration of LET could be effective in inhibiting the production of estradiol, increasing the amount of testosterone, and thus changing the sex ratio of rainbow trout.
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نوع مطالعه: پژوهشي | موضوع مقاله: Genetics
دریافت: 1400/12/19 | پذیرش: 1401/7/12 | انتشار: 1401/12/3
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Alijani H, Amini Chermahini M, Zargham D, Mohiseni M. Research Article: The effect of Letrozole and Letrozole-Chitosan nanoparticles on masculinization of Rainbow trout larvae (Oncorhynchus mykiss). IJFS 2022; 21 (6) :1383-1396
URL: http://jifro.ir/article-1-5006-fa.html

Research Article: The effect of Letrozole and Letrozole-Chitosan nanoparticles on masculinization of Rainbow trout larvae (Oncorhynchus mykiss). مجله علوم شیلاتی ایران. 1401; 21 (6) :1383-1396

URL: http://jifro.ir/article-1-5006-fa.html



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دوره 21، شماره 6 - ( 1401 ) برگشت به فهرست نسخه ها
Iranian Journal of Fisheries Sciences Iranian Journal of Fisheries Sciences
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