en Biochemistry Biochemistry پژوهشي Orginal research papers <p>The purpose of this study was to investigate the therapeutic effects of propolis on biochemical and microbiological parameters in muscle tissues of carp (<em>Cyprinus carpio</em>, Linnaeus 1758) exposed to arsenic. A sublethal concentration of arsenic (0.01 ppm) and/or 0.01 ppm propolis were administered to fish for seven days. Biochemical parameters [pH, lactic acid, total volatile basic nitrogen (TVB-N), and malondialdehyde (MDA) values] and microbiological changes (mesophilic and psychrophilic bacteria count) were determined in fillet of carp in control, arsenic only, propolis only and arsenic+propolis treatment groups. Results showed that the levels of MDA, lactic acid and TVB-N increased (<em>p</em><0.05) while there were decreases total counts of psychrophilic, mesophilic bacteria and level of pH in arsenic group compared to the control group. Additionally, levels of pH, lactic acid, TVB-N, counts of psychrophilic and mesophilic bacteria in arsenic (0.01 ppm)+propolis (10 ppm) group significantly reduced compared to arsenic group (<em>p<</em>0.05). In conclusion, propolis can affects some biochemical and microbiologic functions and quality in the fillet of carp exposed to arsenic. </p> Arsenic, Biochemical parameter, Carp, Fillet, Microbiological analysis, Propolis 896 907 http://jifro.ir/browse.php?a_code=A-10-470-6&slc_lang=en&sid=1 Z Selamoglu zselamoglu@nigde.edu.tr 100319475328460014797 100319475328460014797 Yes A Duran 100319475328460014798 100319475328460014798 No M.F Gulhan 100319475328460014799 100319475328460014799 No M.E Erdemli 100319475328460014800 100319475328460014800 No