en Ecology Ecology پژوهشي Orginal research papers <font face="Times New Roman" size="3"> </font><p class="MsoNormal" style="margin: 0cm 0cm 0pt line-height: 120%"><span style="line-height: 120% font-family: "Times New Roman","serif" font-size: 12pt"><font size="2">Concentration of heavy and toxic metals Cu, Zn, Cd, Pb and Hg were determined in liver and muscles of <i>Rutilus frisii kutum</i> and their relationships with growth parameters (length, age, condition factor) and hepatosomatic index were examined. Thirty-six fish samples were collected from February through March 2009 caught by beach seine in the southwest parts of the Caspian Sea. Atomic absorption and Hg determined concentrations of Cd, Pb, Zn and Cu by vapor method. Cadmium was recorded only in liver samples. Range of other metals in muscle tissue were ND -0.591, 0.001-0.013, 11- 26 and 0.729 -7.261 µg.g^-1dw for Pb, Hg, Zn and Cu respectively. Highest levels of Pb, Zn, and Cu were recorded in muscles Hg and Cd in liver samples. Growth parameters showed a significant relationship with Zn and Cd concentrations in liver samples and only Zn concentrations in muscle samples. There was a positive significant correlation between concentration of Cd in liver and physiological indices</font><font face="Times New Roman"><font size="2"><span style="color: red"> </span>(p<0.05).</font><font size="3"> Although higher concentration of Pb was recorded in this study in comparison to previous studies, based on Provisional Tolerable Weekly and daily Intake of fish for human health, kutum is considered safe for human consumption. Considering the results of this study it seems reproductive status of the fish influences heavy metals concentration in liver and muscles of kutum and therefore concentrations of some metals such as Zn and Cu in liver samples may not be a reliable bioindicator for environmental pollution. <o:p /></font></font></span></p><font face="Times New Roman" size="3"> </font> Rutilus frisii kutum, Caspian Sea, Reproduction, Growth, Condition factor, HSI 825 839 http://jifro.ir/browse.php?a_code=A-10-1-202&slc_lang=en&sid=1 F. Monsefrad javidiman@gmail.com 10031947532846004747 10031947532846004747 Yes J. Imanpour Namin 10031947532846004748 10031947532846004748 No S. Heidary 10031947532846004749 10031947532846004749 No