en Toxicology Toxicology پژوهشي Orginal research papers <p style="margin: 0in 0in 10pt 0.25in; text-align: justify; line-height: 200%; -ms-text-justify: kashida; text-kashida: 0%;"><span style="font-size:11pt"><span style="line-height:120%"><span style="font-family:Calibri,sans-serif"><span lang="TR" style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black">Aluminum (Al) is a major concern in acidic environments as it can lead to the accumulation of reactive oxygen species (ROS), which induce oxidative stress in the host. Assessment of Al-resistant microorganisms can help scientists to discover their mechanisms and improve bioremediation techniques. The present study aimed to characterize Al-resistant microalgae by screening industrial wastewater microorganisms. The microalgae were treated with 0, 10, and 100 &micro;M Al. Then, H₂O₂, malondialdehyde (MDA), catalase (CAT), and peroxidase (POX) values were measured. In addition, the effects of time (30-300 min), Al concentration (0-370 &micro;M), and pH (4.0-6.5) on Al removal were investigated <a name="_Hlk91949024">using the design-expert software</a>. The efficiency of various biosorbents in Al removal was also evaluated in the optimal conditions of the final experiment. According to the results, <i>Scenedesmus </i>sp. was the most resistant microalgae and produced more biomass at 100 &micro;M. Moreover, the POX and CAT activities of <i>Scenedesmus </i>sp. were increased by the high Al concentrations. In optimum conditions (81.60 &micro;M Al, pH 5.8, 45 minutes), free cells (without modifications) were effective in Al biosorption (93.56%).</span></span></span></span></span></span></span></p> Aluminum, Antioxidant, Bioremediation, Scenedesmus, Oxidative stress 178 195 http://jifro.ir/browse.php?a_code=A-10-3615-1&slc_lang=en&sid=1 M. Ameri ma.ameri65@gmail.com 100319475328460047126 100319475328460047126 Yes Industrial Microbial Biotechnology Department, Research Institute for Industrial Biotechnology, Academic Center for Education, Culture and Research (ACECR) Mashhad, Iran and Department of Plant Sciences, Faculty of Biological Sciences, Kharazmi University, Tehran, Iran R.A. Khavari-Nejad ra.khavarinejad@ 100319475328460047127 100319475328460047127 No Department of Plant Sciences, Faculty of Biological Sciences, Kharazmi University, Tehran, Iran N. Soltani soltani6@yahoo.com 100319475328460047128 100319475328460047128 No Department of Petroleum Microbiology, Research Institute of Applied Science, ACECR, Tehran., Iran F. Najafi Farzaneh.najafi1@gml.com 100319475328460047129 100319475328460047129 No Department of Plant Sciences, Faculty of Biological Sciences, Kharazmi University, Tehran, Iran A. Bagheri bagheriyazd@gmail.com 100319475328460047130 100319475328460047130 No Faculty of Agriculture, Ferdowsi University of Mashhad, Iran M. Seyedabadi 100319475328460047131 100319475328460047131 No Industrial Microbial Biotechnology Department, Research Institute for Industrial Biotechnology, Academic Center for Education, Culture and Research (ACECR) Mashhad, Iran and Department of Plant Sciences, Faculty of Biological Sciences, Kharazmi University, Tehran, Iran