Iranian Journal of Fisheries Sciences
مجله علوم شیلاتی ایران
IJFS
Agriculture
http://jifro.ir
1
admin
1562-2916
10.18869/acadpub.ijfs
en
jalali
1400
2
1
gregorian
2021
5
1
20
3
online
1
fulltext
en
Research Article: Histological study and evaluation of Hsp70 gene expression in gill and liver tissues of goldfish (Carassius auratus) exposed to Zinc oxide nanoparticles
Genetics
Genetics
پژوهشي
Orginal research papers
In parallel with the increased use of nano-sized metallic materials, the possibility of their release into the environment has increased in recent decades. However, there is not sufficient information on the toxic potential of these materials on different aspects of the life history of aquatic organisms. In this study, we investigated the impact of zinc oxide nanoparticles (ZnO-NPs) on goldfish by studying histopathological alteration and Hsp70 gene expression in gill and liver tissues. The results showed that after exposure to different concentrations of ZnO-NPs, severe lesions were observed in the gill and liver tissues of goldfish. Expression of Hsp70 significantly increased in comparison with the control group and this increase was observed especially in the initial sampling times. Also expression pattern of Hsp70 is relatively similar in gill and liver tissues of goldfish. Based on the results of the present study, ZnO-NPs, as widely used nanoparticles can endanger the health of goldfish and further studies are needed to evaluate its potential toxic effects.
ZnO-NPs, Gene expression, Histopathology, Toxicity, Goldfish
741
760
http://jifro.ir/browse.php?a_code=A-10-2717-1&slc_lang=en&sid=1
M.
Harsij
m_harsij800@yahoo.com
100319475328460040317
100319475328460040317
Yes
Department of Fishery, Gonbad University of Agricultural Sciences and Natural Resources, Gonbad, Iran
H.
Paknejad
hkolangi@yahoo.com
100319475328460040318
100319475328460040318
No
Department of Fishery, Gonbad University of Agricultural Sciences and Natural Resources, Gonbad, Iran
M.
Khalili
Khalili@gmail.com
100319475328460040319
100319475328460040319
No
Cellular and Molecular Research Center, Golestan University of Medical Sciences, Gorgan, Iran.
H.
Jafarian
Jafarian@gmail.com
100319475328460040320
100319475328460040320
No
Department of Fishery, Gonbad University of Agricultural Sciences and Natural Resources, Gonbad, Iran
S.
Nazari
nazarisajad92@gmail.com
100319475328460040321
100319475328460040321
No
Cold-water Fishes Genetic and Breeding Research Center, Iranian Fisheries Research Institute, Agricultural Research, Education and Extension Organization (AREEO), Yasouj, Iran