en aquaculture aquaculture پژوهشي Orginal research papers <p>This study aimed at determining blood biochemical parameters with potential diagnostic value to assess the nutritional status for healthy Snow trout,<em> Schizothorax zarudnyi</em>. For this purpose, three treatment groups of Snow trout (average weight, 65.9&plusmn;5.3 g) were kept unfed for 24 h, 7 and 14 days. During the experiment, a natural photoperiod was adopted, water temperature was maintained at 23.2&plusmn;1.1 &deg;C, pH at 7.8&plusmn;0.2, dissolved oxygen at 7&plusmn;0.4 mg L^-1 and ammonia concentration was kept around zero mg L^-1. Fish in all treatment groups were fed twice a day, to apparent satiety. At the end of the trial, the levels of glucose; triglyceride; cholesterol; total protein; inorganic phosphorus; calcium; magnesium; triiodothyronine (T₃); thyroxin (T₄); alkaline phosphatase (ALP); aspartate aminotransferase (AST); Alanine aminotransferase ( ALT ) and lactate dehydrogenase (LDH) were determined using standard clinical methods. The results showed that glucose (71.8&plusmn;6.64-138.6&plusmn;13.02 mg dl^-1), AST (63.53&plusmn;12.17-130.41&plusmn;23.04Ul^-1) and T₄ (6.46&plusmn;0.88-11.69&plusmn;1.16 ng ml^-1) levels were significantly affected by the starvation period (<em>p</em><0.05). T₃ levels remained relatively stable during the first week of starvation (2.3&plusmn;0.25-2.39&plusmn;0.31 ng ml^-1) and then significantly decreased (1.77&plusmn;0.16 ng ml^-1) in the second week of starvation (<em>p</em><0.05). Triglycerides levels increased during the first week of starvation (147.40&plusmn;16.62 to 199.31&plusmn;31.42 mg dl^-1) and decreased significantly (<em>p</em><0.05) in the second week (163.70&plusmn;24.63 mg dl^-1). These results suggested that in healthy Snow trout juveniles, glucose, AST and T₄ levels are responsive to starvation.</p> Blood biochemistry, Thyroid hormone, Enzymes activity, Schizothorax zarudnyi, Starvation 735 744 http://jifro.ir/browse.php?a_code=A-10-2093-2&slc_lang=en&sid=1 H khandan Barani hashem.barani94@gmail.com 100319475328460030895 100319475328460030895 Yes Department of Fisheries, Hamoun International Wetland Research Institute, University of Zabol, Zabol, Iran A Gharaei Agharaei551@uoz.ac.ir 100319475328460030896 100319475328460030896 No Department of Fisheries, Hamoun International Wetland Research Institute, University of Zabol, Zabol, Iran N Sanchooli narjessanchooli@uoz.ac.ir 100319475328460030897 100319475328460030897 No Department of Fisheries, Hamoun International Wetland Research Institute, University of Zabol, Zabol, Iran M Miri mirimohadeseh@uoz.ac.ir 100319475328460030898 100319475328460030898 No Department of Natural ecosystems management, Hamoun International Wetland Research Institute, University of Zabol, Zabol, Iran