fa Genetics Genetics پژوهشي Orginal research papers <p>The current study evaluated effects of dietary administration doses of <em>Entrococcus faecium</em> on the hematological factors, and disease resistance of <em>Sander lucioperca</em> against <em>Aeromonas hydrophila</em> infection. Fish were fed with dietary administration containing <em>E. faecium</em> doses including of (10¹⁰, 10⁸CFU/ g) for diet A₁ and A₂, respectively in a commercial diet as basal diet were used for 6 weeks<strong>. </strong>The control group was basal diet with serum. The hematological and immunity parameters were measured and fish were challenged with<em> A.hydrophila</em> (4.5&times;10⁸CFU/mL). Fish were monitored daily and the mortality rates were recorded over 8 days post &ndash; challenge. The results indicated that HCT in A₁ treatment (10¹⁰CFU/g) had significantly increased in compare to the control and A₂ (10⁸ CFU/g) treatments (<em>p</em><0.05). &nbsp;MCV in A₁(10¹⁰CFU/g) and control groups were significantly higher than A₂ (10⁸ CFU/g) Treatment (<em>p</em><0.05). However, other parameters e.g. RBC, HB, MCH, MCHC had no significant different. The serum lysozyme, alternative complement activity (ACH50) and IgM levels were significantly enhanced in dietary administration<em> E. faecium</em>(10⁸,10¹⁰CFU/g) in feeding period. Survival rate of fish by dietary administration <em>E. faecium</em> (10¹⁰CFU/g) was significantly higher (<em>p</em><0.05) than the other groups (86.6%).</p> <p></p> Entrococcus faecium, Aeromonas hydrophila, Hematology, Immunity 1581 1592 http://jifro.ir/browse.php?a_code=A-10-600-41&slc_lang=fa&sid=1 M. Faeed 100319475328460019914 100319475328460019914 No R. Kasra Kermanshahi rkasra@yahoo.com 100319475328460019915 100319475328460019915 Yes M. Pourkazemi 100319475328460019916 100319475328460019916 No M. Darboee 100319475328460019917 100319475328460019917 No S. Haghighi Karsidani 100319475328460019918 100319475328460019918 No