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Study on the potency of domperidone and metoclopramide for spawning induction in Kutum (Rutilus frisii kutum )
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F. Peykan Heyrati   , S. Dorafshan * |
| , dorafshan@modares.ac.ir |
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Abstract: (3651 Views) |
The effectiveness of two kinds of dopamine antagonist (DA), metoclopramide (Met) and domperidone (Dom) combined with the gonadotropin releasing hormone analogue (D-Ala6, Des Gly10 ethylamide) GnRHa was assayed on the ovulation success, latency period, ovulation index (OI) and fertilization success of kutum, Rutilus frisii kutum (Kamenskii, 1901). Brood fish were injected intra-peritoneally as follows: 2 mg/kg b.w. of carp pituitary extract (CPE) as a control, 5 g+ 2.5mg, 1mg+ 5mg and 2mg+ 10mg/kg b.w. of GnRHa + Met or Dom in a single injection.
Based on the ovulation and fertilization success, no significant differences between similar doses of Dom and Met when combined with similar doses of GnRHa were found (p>0.05). However, in some groups, the OI and latency period were greater when Dom was used as a DA instead of Met (p<0.05). In general, the results of this study showed that the potency of Dom was nearly same as Met when combined with GnRHa and used as a DA in kutum. It is strongly recommended to repeat the experiment under different conditions to find out definite conclusion. |
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| Keywords: Kutum, Rutilus frisii kutum, Spawning, GnRHa, metoclopramide, domperidone |
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Full-Text [PDF 2309 kb]
(1161 Downloads)
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Type of Study: Orginal research papers |
Subject:
Biology & physiology
Received: 2017/12/9 | Accepted: 2017/12/9 | Published: 2017/12/9
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