en aquaculture aquaculture كاربردي Orginal research papers <span style="font-size:10pt"><span style="background:white"><span style="line-height:normal"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><span style="font-size:12.0pt"><span style="color:black">Prosopis </span></span></span></span></span></span></span><span lang="TR" style="font-size:11.0pt"><span calibri="" style="font-family:"><span style="color:black">species, particularly <i>Prosopis juliflora</i> are known for their antioxidant, anti-inflammatory, antibacterial, and antifungal properties. The present study evaluated the effect of three doses of dietary ethanolic leaf extract of <i>P. juliflora</i> (ELEPJ), i.e., 0.25, 0.5, and 1% on the immune- antioxidant system and the resistance to cold water stress in Pacific white shrimp, <i>Litopenaeus vannamei</i>. After 60 days of the feeding trial, the shrimps fed diets containing 0.5 and 1% ELEPJ showed significantly higher lysozyme activity, superoxide dismutase, phenol oxidase, and glutathione peroxidase than those of the control group (<i>p</i><0.05). In response to the cold water stress, the shrimp fed diets containing 0.5 and 1% of ELEPJ showed significantly higher stress resistance than the control group. These results suggest the positive effects of ELEPJ on the immune-antioxidant system and stress resistance of <i>L. vannamei</i> and supplementation of 0.5-1% ELEPJ is recommended for the farm-raised shrimp diet.</span></span></span> Whiteleg shrimp, Prosopis juliflora, Hemolymph, Immune-antioxidant system, Stress 473 484 http://jifro.ir/browse.php?a_code=A-10-4561-2&slc_lang=en&sid=1 M. Zabolinia masoumeh.zabolinia@gmail.com 100319475328460051366 100319475328460051366 No Department of Fisheries, Faculty of Marine Science and Technology, University of Hormozgan, Bandar Abbas, Iran L. Abdoli l.abdoli@hormozgan.ac.ir 100319475328460051367 100319475328460051367 Yes Department of Fisheries, Faculty of Marine Science and Technology, University of Hormozgan, Bandar Abbas, Iran A. Akbarzadeh akbarzadeh@hormozgan.ac.ir 100319475328460051368 100319475328460051368 No Department of Fisheries, Faculty of Marine Science and Technology, University of Hormozgan, Bandar Abbas, Iran