en fish disease fish disease گزارش مورد Review paper <span lang="TR" style="font-size:11.0pt"><span calibri="" style="font-family:"><span style="color:black">Cyprinid herpesvirus 3 (CyHV-3) is a significant threat to the production of common carp and koi, resulting in high mortality rates and posing a risk to the long-term sustainability of carp aquaculture. The presence of this disease in Iran has been confirmed by the veterinary organization and reported to OIE, with evidence suggesting its presence since 2021 in Iranian Koi and carp farms. Given the economic importance and rapid spread of CyHV-3, this review aims to provide a comprehensive summary of the current knowledge and research on the virus and its disease in Iran and worldwide.&nbsp; The fish farmers and authorities in the country need to take necessary measures to prevent the spread of the disease and mitigate its impact on the aquaculture industry.</span></span></span> Koi Herpesvirus, CyHV-3, Koi, Common carp, KHVD, Iran 783 802 http://jifro.ir/browse.php?a_code=A-10-795-2&slc_lang=en&sid=1 M. Bavarsad M.bavarsad@ut.ac.ir 100319475328460056610 100319475328460056610 No Department of Fisheries and Environmental Sciences, Faculty of Natural Resources, University of Tehran, Iran A. Abed-Elmdoust amirabed@ut.ac.ir 100319475328460056611 100319475328460056611 No Department of Fisheries and Environmental Sciences, Faculty of Natural Resources, University of Tehran, Iran M.R. Tabandeh m.tabandeh@scu.ac.ir 100319475328460056612 100319475328460056612 No Department of Biochemistry and Molecular Biology, Faculty of Veterinary Medicine, Shahid Chamran University of Ahvaz, Iran H. Farahmand hfarahmand@ut.ac.ir 100319475328460056613 100319475328460056613 No Department of Fisheries and Environmental Sciences, Faculty of Natural Resources, University of Tehran, Iran M. Alishahi alishahim@scu.ac.ir 100319475328460056614 100319475328460056614 No Department of Clinical Sciences, Faculty of Veterinary Medicine, Shahid ChamranUniversity of Ahvaz, Iran A. Mirvaghefi avaghefi@ut.ac.ir 100319475328460056615 100319475328460056615 No Department of Fisheries and Environmental Sciences, Faculty of Natural Resources, University of Tehran, Iran A. Avazeh amin.avazeh@ut.ac.ir 100319475328460056616 100319475328460056616 No Department of Fisheries and Environmental Sciences, Faculty of Natural Resources, University of Tehran, Iran M. Adel 100319475328460056617 100319475328460056617 Yes Iranian Fisheries Science Research Institute (IFSRI), Agricultural Research Education and Extension Organization (AREEO), Tehran, Iran A. Jafari arman_j86@yahoo.com 100319475328460056618 100319475328460056618 No Department of Fisheries, Sari Agricultural Sciences and Natural Resources University, Sari, Iran M.J. Zorriehzahra zorrieh@yahoo.com 100319475328460056619 100319475328460056619 No Iranian Fisheries Science Research Institute (IFSRI), Agricultural Research Education and Extension Organization (AREEO), Tehran, Iran T. Citarasu citarasu@gmail.com 100319475328460056620 100319475328460056620 No Centre for Marine Science and Technology, Manonmaniam Sundaranar University, Rajakkamangalam, Kanyakumari, Tamilnadu 629502, India