en aquaculture aquaculture پژوهشي Orginal research papers <span style="font-size:11pt"><span style="line-height:120%"><span style="font-family:Calibri,sans-serif"><span lang="TR" style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black">This study was done to find the effect of different levels of curcumin on growth performance, </span></span></span></span><span lang="TR" style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black">immune response, and hematological</span></span></span></span><span lang="TR" style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black"> markers in Siberian sturgeon, <i>Acipenser baerii</i>. For this purpose, a total number of 120 Siberian sturgeons with an average initial weight of 55.05&plusmn;0.03 g (means&plusmn;SD) were distributed into 12 tanks with 10 fish per tank (4 treatments with 3 replications) and fed four diets supplemented with 0 (base group, (C0), 0.5 (C0.5), 1 (C1), and 1.5 (C1.5) g kg^-1curcumin at </span></span></span></span><span lang="TR" style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black">2.5% of body weight three times a day </span></span></span></span><span lang="TR" style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black">for 8 weeks. The highest </span></span></span></span><span lang="TR" style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black">final body weight (83.10 g), specific growth rate (3.12</span></span></span></span><span lang="TR" style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black">% day ^-1</span></span></span></span><span lang="TR" style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black">), and body weight increase (51.1%) were obtained in the fish fed with 1 g kg^&minus;1 curcumin (<i>p</i><0.05)</span></span></span></span><span lang="TR" style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black">. The highest number of red blood cells and white blood cells were measured in C1 treatment. The immune responses were significantly influenced by different curcumin levels in the diets (<i>p</i><0.05). The a</span></span></span></span><span lang="TR" style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black">lternative complement pathway</span></span></span></span><span lang="TR" style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black">, lysozyme, and </span></span></span></span><span lang="TR" style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black">respiratory burst activity were </span></span></span></span><span lang="TR" style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black">significantly increased, especially in the fish fed with 1 g kg^-1 curcumin. </span></span></span></span><span lang="TR" style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black">In conclusion, the results indicated that 1 g kg^-1 curcumin notably enhances growth and non-specific immune responses in </span></span></span></span><span lang="TR" style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black">Siberian sturgeon.</span></span></span></span></span></span></span> Acipenser baerii, Herbal extract, Growth, Immune response 1265 1276 http://jifro.ir/browse.php?a_code=A-10-3722-2&slc_lang=en&sid=1 Z. Behbodi zahra.behbodu989@yahoo.com 100319475328460051235 100319475328460051235 No Department of Fisheries, Qaemshahr Branch, Islamic Azad University, Qaemshahr, Iran S. Bahram bahramsomi@gmail.com 100319475328460051236 100319475328460051236 Yes Department of Fisheries, Qaemshahr Branch, Islamic Azad University, Qaemshahr, Iran S.R. Javadian Ro.javadian@gmail.com* 100319475328460051237 100319475328460051237 No Department of Fisheries, Qaemshahr Branch, Islamic Azad University, Qaemshahr, Iran