fa fish disease fish disease پژوهشي Orginal research papers <p>The present study was done to evaluate the presence of antibiotic resistance genes in <em>Lactococcus garvieae</em> isolated from cultured rainbow trout, West Iran.The isolates were examined for antimicrobial resistance using disc diffusion method. Of the 24 strains tested, 21 were resistant to ampicillin (87.5%), 9 to erythromycin (37.5%) and 19 to tetracycline (79.1%). Fourteen strains were resistant to four antibiotics, 8 resistant to five antibiotics and 2 to six antibiotics.The strains&nbsp;<em>were</em>&nbsp;also characterized for their genotypic&nbsp;<em>resistance </em>profiles.&nbsp;The results revealed that all 24 isolates contained one to three of the antibiotic resistance genes. <em>StrA</em>, <em>tetS</em> and <em>ermB</em> genes coding for streptomycin, tetracycline and erythromycin resistance were found in 7, 10 and 9 isolates, respectively and sulfamethoxazole resistance gene, <em>sul2</em>, was not detected in the examined isolates. High levels of antibiotic resistance and detection of resistance genes in <em>L. garvieae </em>strains should be considered as a potential danger for trout culture as well as for public health.</p> Lactococcus garvieae, Antimicrobial resistance genes, Rainbow trout. 221 229 http://jifro.ir/browse.php?a_code=A-10-10-4&slc_lang=fa&sid=1 M Raissy mehdi.raissy@iaushk.ac.ir 100319475328460015214 100319475328460015214 Yes M Moumeni 100319475328460015215 100319475328460015215 No