AU - Peykan Heyrati, F. AU - Dorafshan, S. TI - Study on the potency of domperidone and metoclopramide for spawning induction in Kutum (Rutilus frisii kutum ) PT - JOURNAL ARTICLE TA - IFRO JN - IFRO VO - 6 VI - 2 IP - 2 4099 - http://jifro.ir/article-1-3105-en.html 4100 - http://jifro.ir/article-1-3105-en.pdf SO - IFRO 2 ABĀ  - The effectiveness of two kinds of dopamine antagonist (DA), metoclopramide (Met) and domperidone (Dom) combined with the gonadotropin releasing hormone analogue (D-Ala6, Des Gly10 ethylamide) GnRHa was assayed on the ovulation success, latency period, ovulation index (OI) and fertilization success of kutum, Rutilus frisii kutum (Kamenskii, 1901). Brood fish were injected intra-peritoneally as follows: 2 mg/kg b.w. of carp pituitary extract (CPE) as a control, 5 g+ 2.5mg, 1mg+ 5mg and 2mg+ 10mg/kg b.w. of GnRHa + Met or Dom in a single injection. Based on the ovulation and fertilization success, no significant differences between similar doses of Dom and Met when combined with similar doses of GnRHa were found (p>0.05). However, in some groups, the OI and latency period were greater when Dom was used as a DA instead of Met (p<0.05). In general, the results of this study showed that the potency of Dom was nearly same as Met when combined with GnRHa and used as a DA in kutum. It is strongly recommended to repeat the experiment under different conditions to find out definite conclusion. CP - IRAN IN - LG - eng PB - IFRO PG - 105 PT - Orginal research papers YR - 2007