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جلد 16 شماره 1 صفحات 200-209 برگشت به فهرست نسخه ها
Antimicrobial activities of semi polar-nonpolar and polar secondary metabolites of sponge Dysidea pallescens from Hengam Island, Persian Gulf
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Sponges are the simplest multicellular animals that lack defense mechanisms and rely on chemical defense  that have been used by mankind to develop antimicrobial drugs against diseases.  The present study was designed to demonstrate the antibacterial and antifungal activities of marine sponge Dysidea pallescens semipolar and nonpolar extracts. In this study, D. pallescens were collected from Hengam Island in the Persian Gulf. The extracts were produced by Bligh and Dyer method. Broth Dilution Methods were used to check the antimicrobial activity of D. pallescens extracts against Escherichia coli (ATCC 15224), Pseudomonas aeruginosa (ATCC 25619), Staphylococcus aureus aureus (ATCC 1764), Bacillus subtilis pizizenii (ATCC 6633), Candida albicans (ATCC10231) and Aspergillus fumigates (PTCC5009). The results showed diethyl ether extract has bactericidal activity against S. aureus aureus (MBC=10mg/mL) and B. subtilis spizizenii (MBC=20mg/mL). D. pallescens diethyl ether extract showed a very weak antifungal activity but methanol extract showed fungicidal activity against A. fumigates (MFC=5mg/mL) and C. albicans (MFC=1.5 mg/mL). Therefore nonpolar-semipolar secondary metabolites of D. pallescens solutions in diethyl ether have shown significant antibacterial activity and polar- secondary metabolites solutions in methanol have shown significant antifungal activity. 

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نوع مطالعه: پژوهشي | موضوع مقاله: Biotechnology
دریافت: ۱۳۹۵/۱۱/۲۶ | پذیرش: ۱۳۹۵/۱۱/۲۶ | انتشار: ۱۳۹۵/۱۱/۲۶
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Nazemi M, Moradi Y, Rezvani Gilkolai F, Ahmaditaba M, Gozari M, Salari Z. Antimicrobial activities of semi polar-nonpolar and polar secondary metabolites of sponge Dysidea pallescens from Hengam Island, Persian Gulf. IJFS. 2017; 16 (1) :200-209
URL: http://jifro.ir/article-1-2586-fa.html
Antimicrobial activities of semi polar-nonpolar and polar secondary metabolites of sponge Dysidea pallescens from Hengam Island, Persian Gulf. مجله علوم شیلاتی ایران. 1395; 16 (1) :200-209

URL: http://jifro.ir/article-1-2586-fa.html

دوره 16، شماره 1 - ( 10-1395 ) برگشت به فهرست نسخه ها
مجله علوم شیلاتی ایران Iranian Journal of Fisheries Sciences
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