en Toxicology Toxicology پژوهشي Orginal research papers <span style="font-size:11pt"><span style="line-height:120%"><span style="text-autospace:none"><span style="font-family:Calibri,sans-serif"><span lang="TR" style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black">Coastal waters in northern part of Hormuz Strait receive large inputs of anthropogenic pollutants. This study was conducted to determine the effects of environmental contaminants on plasma enzymes, thyroid hormones and biochemical blood parameters of </span></span></span></span><i><span lang="IT" style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black">Periophthalmus argentilineatus</span></span></span></span></i><b> </b><span lang="TR" style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black">to monitor marine pollution from northern part of Hormuz strait. For this purpose, </span></span></span></span><span lang="TR" style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black">a total of 90 specimens were collected </span></span></span></span><span lang="TR" style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black">from three estuarine stations (</span></span></span></span><span lang="TR" style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black">30 specimens for each station)</span></span></span></span><span lang="TR" style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black"> including Shour-e-aval (first station; St₁), Souro (second station; St₂) and Bustanoo (third station; St₃) and some blood plasma indices, </span></span></span></span><span lang="TR" style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black">such as aspartate </span></span></span></span><span lang="TR" style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black">amino</span></span></span></span><span lang="TR" style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black">transaminase </span></span></span></span><span lang="TR" style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black">(AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), lactate dehydrogenase (LDH), glucose (GLU), cholesterol (CHOL), triglyceride (TRIG), and thyroid hormones including triiodothyronine (T₃), thyroxine (T₄) and thyroid-stimulating hormone (TSH) were measured. Results showed that the plasma enzymes levels were significantly higher in fish from the polluted location (Bustanoo; station 3). Concentrations of<b> </b>thyroid hormones and also the glucose and cholesterol levels were significantly higher in the samples from the station 3 (<i>p</i><0.05). Due to the negative impact of pollutants on biochemical and hormonal functions of blood serum of resident species, including </span></span></span></span><i><span lang="IT" style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black">P. argentilineatus</span></span></span></span></i><span lang="TR" style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black">, this species can be used as a bioindicator of pollution in northern part of Hormuz Strait.</span></span></span></span></span></span></span></span> Hormuz Strait, Anthropogenic pollutants, Periophthalmus argentilineatus, Bioindicator, Biochemical blood parameters, Thyroid hormones 431 444 http://jifro.ir/browse.php?a_code=A-10-3235-1&slc_lang=en&sid=1 M. Kerdgari m_kerdgar@gmail.com 100319475328460045544 100319475328460045544 No Young researches and Elite club, Islamic Azad University, Bandar Abbas branch, P.O. Box: 79159-1311, Bandar Abbas, Iran. M. Afkhami m_afkhami82@yahoo.com 100319475328460045545 100319475328460045545 No Young researches and Elite club, Islamic Azad University, Bandar Abbas branch, P.O. Box: 79159-1311, Bandar Abbas, Iran. M. Ehsanpour mehsanpour@yahoo.com 100319475328460045546 100319475328460045546 No Young researches and Elite club, Islamic Azad University, Bandar Abbas branch, P.O. Box: 79159-1311, Bandar Abbas, Iran. M. Ghanbarzadeh mehrna.ghanbarzadeh@gmail.com 100319475328460045547 100319475328460045547 Yes Department of Marine biology, Faculty of Marine Sciences and Technologies, University of Hormozgan, Bandar Abbas, Iran. P.O. Box 3995